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CAPZA1

CAPZA1 (Capping Actin Protein Of Muscle Z-Line Alpha Subunit 1) is a Protein Coding gene. Diseases associated with CAPZA1 include Autosomal Recessive Primary Microcephaly. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is CAPZA2.
Full Name
Capping Actin Protein Of Muscle Z-Line Alpha Subunit 1
Function
F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions.
Biological Process
Actin cytoskeleton organization Source: GO_Central
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Barbed-end actin filament capping Source: GO_Central
Blood coagulation Source: Reactome
Cell junction assembly Source: UniProtKB
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Innate immune response Source: Reactome
Interleukin-12-mediated signaling pathway Source: Reactome
Protein-containing complex assembly Source: ProtInc
Cellular Location
Cytoskeleton

Anti-CAPZA1 antibodies

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Mouse Anti-CAPZA1 Recombinant Antibody (CBYY-C0941) (CBMAB-C2378-YY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Rat
Clone: CBYY-C0941
Application*: WB

Mouse Anti-CAPZA1 Recombinant Antibody (CBLC096-LY) (CBMAB-C9698-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBLC096-LY
Application*: E, WB, P

Mouse Anti-CAPZA1 Recombinant Antibody (CBLC097-LY) (CBMAB-C9699-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLC097-LY
Application*: E, WB

Mouse Anti-CAPZA1 Recombinant Antibody (49) (CBMAB-AP774LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 49
Application*: ELISA, IF, WB

Mouse Anti-CAPZA1 Recombinant Antibody (EG474) (CBMAB-EN538-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: EG474
Application*: ELISA, WB

Mouse Anti-CAPZA1 Recombinant Antibody (EG475) (CBMAB-EN539-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: EG475
Application*: ELISA, WB

Mouse Anti-CAPZA1 Recombinant Antibody (CBFYC-0805) (CBMAB-C0860-FY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYC-0805
Application*: siRNA, E, IF, WB

Mouse Anti-CAPZA1 Recombinant Antibody (CBXC-2353) (CBMAB-C5145-CQ)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBXC-2353
Application*: IR, E, IF, WB

Mouse Anti-CAPZA1 Recombinant Antibody (CBXC-2300) (CBMAB-C5146-CQ)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2300
Application*: WB

Mouse Anti-CAPZA1 Recombinant Antibody (CF060) (CBMAB-FT417LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF060
Application*: ELISA, WB, IF

Mouse Anti-CAPZA1 Recombinant Antibody (10H1F9) (CBMAB-C2350-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 10H1F9
Application*: E, IF, WB

Mouse Anti-CAPZA1 Recombinant Antibody (2) (CBMAB-C4301-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2
Application*: WB, E, P

Mouse Anti-CAPZA1 Recombinant Antibody (2G4) (CBMAB-C5178-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G4
Application*: F, IH, P, WB

Mouse Anti-CAPZA1 Recombinant Antibody (7C8) (CBMAB-C8602-LY)

Datasheet SDS
Target: CAPZA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Rat
Clone: 7C8
Application*: WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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