CCT7

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date. [provided by RefSeq]
Full Name
chaperonin containing TCP1, subunit 7 (eta)
Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444).
The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Biological Process
Binding of sperm to zona pellucida Source: Ensembl
Positive regulation of establishment of protein localization to telomere Source: BHF-UCL
Positive regulation of protein localization to Cajal body Source: BHF-UCL
Positive regulation of telomerase RNA localization to Cajal body Source: BHF-UCL
Positive regulation of telomere maintenance via telomerase Source: BHF-UCL
Protein folding Source: FlyBase
Protein stabilization Source: BHF-UCL
Toxin transport Source: Ensembl
Cellular Location
Cytoplasm
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Anti-CCT7 antibodies

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Rat Anti-CCT7 Recombinant Antibody (PK/16/8/a) (CBMAB-C9967-LY)

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Target: CCT7
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rabbit, Cattle
Clone: PK/16/8/a
Application*: WB, P
Datasheet SDS

Mouse Anti-CCT7 Recombinant Antibody (CBXC-0169) (CBMAB-C5668-CQ)

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Target: CCT7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Horse, Rat, Cattle, Dog, Pig
Clone: CBXC-0169
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CCT7 Recombinant Antibody (CBYJT-1083) (CBMAB-T0093-YJ)

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Target: CCT7
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Horse, Rat, Cattle, Dog, Pig
Clone: CBYJT-1083
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CCT7 Recombinant Antibody (CBYJT-1082) (CBMAB-T0092-YJ)

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Target: CCT7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Horse, Rat, Cattle, Dog, Pig
Clone: CBYJT-1082
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CCT7 Recombinant Antibody (CBFYC-1097) (CBMAB-C1154-FY)

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Target: CCT7
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1097
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CCT7 Recombinant Antibody (1D6) (CBMAB-C5659-LY)

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Target: CCT7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 1D6
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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