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Rat Anti-CCT7 Recombinant Antibody (CBYJT-1083) (CBMAB-T0093-YJ)

Provided herein is a Rat monoclonal antibody, which binds to CCT7 (Chaperonin Containing TCP1 Subunit 7). The antibody can be used for immunoassay techniques, such as WB, IHC, IHC-P.
See all CCT7 antibodies

Summary

Host Animal
Rat
Specificity
Human, Mouse, Cattle, Rabbit
Clone
CBYJT-1083
Antibody Isotype
IgG2a
Application
WB, IHC, IHC-P

Basic Information

Immunogen
Made to CCT ETA
Specificity
Human, Mouse, Cattle, Rabbit
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
chaperonin containing TCP1, subunit 7 (eta)
Introduction
CCT7 (Chaperonin Containing TCP1 Subunit 7) is a Protein Coding gene. Diseases related to CCT7 include Myocardial Infarction and Babesiosis. Among its related pathways are Chaperonin-mediated protein folding and Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding. Gene Ontology (GO) annotations related to CCT7 include identical protein binding and unfolded protein binding.
Entrez Gene ID
Human10574
Mouse12468
Cattle514355
Rabbit100009372
UniProt ID
HumanQ99832
MouseP80313
CattleQ2NKZ1
RabbitG1U9T1
Alternative Names
Chaperonin Containing TCP1 Subunit 7; TCP-1-Eta; CCT-Eta; NIP7-1; CCTH; Chaperonin Containing T-Complex Polypeptide 1, Eta Subunit; Chaperonin Containing TCP1, Subunit 7 (Eta)
Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444).
The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Biological Process
Binding of sperm to zona pellucida Source: Ensembl
Positive regulation of establishment of protein localization to telomere Source: BHF-UCL
Positive regulation of protein localization to Cajal body Source: BHF-UCL
Positive regulation of telomerase RNA localization to Cajal body Source: BHF-UCL
Positive regulation of telomere maintenance via telomerase Source: BHF-UCL
Protein folding Source: FlyBase
Protein stabilization Source: BHF-UCL
Toxin transport Source: Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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