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CD8

CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 consists of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Alpha and beta chains have a strong homology to immunoglobulins with variable light channels. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. The alpha chains of CD8 bind to the alpha domains of classI MHC molecules, alpha 3.
Full Name
Cluster of differentiation 8
Alternative Names
CD8

Anti-CD8 antibodies

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Mouse Anti-CD8 Recombinant Antibody (C1083) (CBMAB-C1083-LY)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: C1083
Application*: IF, IP, WB, F
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (0999) (CBMAB-0999-LY)

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Target: CD8 (Lyt 2.1)
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: 0999
Application*: WB, in vivo
In Vivo Assay
Datasheet SDS

Rat Anti-CD8 Recombinant Antibody (AG40) (V2LY-0524-LY115)

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Target: CD8
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: AG40
Application*: F, C, WB
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (CBT4602) (V2LY-0625-LY2085)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4602
Application*: WB
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (CBT2729) (V2LY-0625-LY2049)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2729
Application*: F
Datasheet SDS

Rabbit Anti-CD8 Recombinant Antibody (80) (CBMAB-C8920-LY)

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Target: CD8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Cat, Human
Clone: 80
Application*: P
Datasheet SDS

Rabbit Anti-CD8 Recombinant Antibody (C7680) (CBMAB-C7680-LY)

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Target: CD8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: C7680
Application*: F
Datasheet SDS

Rat Anti-CD8 Recombinant Antibody (C6365) (CBMAB-C6365-LY)

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Target: CD8
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: C6365
Application*: in vivo, FC, WB, IF
In Vivo Assay
Datasheet SDS

Rabbit Anti-CD8 Recombinant Antibody (C2337) (CBMAB-C2337-LY)

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Target: CD8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: C2337
Application*: E, P
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (C1375) (CBMAB-C1375-LY)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C1375
Application*: IF, F, P
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (C1357) (CBMAB-C1357-LY)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C1357
Application*: IF, F, P
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (37006) (CBMAB-C1033-LY)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: 37006
Application*: IF, IP, WB, F, P
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (C0978) (CBMAB-C0978-LY)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: C0978
Application*: F, in vivo
In Vivo Assay
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (C0799) (CBMAB-C0799-LY)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: C0799
Application*: in vivo, FC, IH
In Vivo Assay
Datasheet SDS

Rat Anti-CD8 Recombinant Antibody (2.43) (CBMAB-C0562-LY)

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Target: CD8
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: 2.43
Application*: WB, in vivo
In Vivo Assay
Datasheet SDS

Mouse Anti-CD8 Recombinant Antibody (C0432) (CBMAB-C0432-LY)

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Target: CD8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: C0432
Application*: WB, in vivo
In Vivo Assay
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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