CDC7
CDC7 (Cell Division Cycle 7) is a Protein Coding gene. Among its related pathways are E2F mediated regulation of DNA replication and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity.
Full Name
Cell Division Cycle 7
Function
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylate MCM2 and MCM3.
Biological Process
Cell cycle phase transition Source: BHF-UCL
Cell division Source: UniProtKB-KW
DNA replication Source: Reactome
DNA replication initiation Source: Reactome
Double-strand break repair via break-induced replication Source: GO_Central
G1/S transition of mitotic cell cycle Source: ProtInc
Negative regulation of G0 to G1 transition Source: Reactome
Peptidyl-serine phosphorylation Source: GO_Central
Positive regulation of cell population proliferation Source: HGNC-UCL
Positive regulation of G2/M transition of mitotic cell cycle Source: UniProtKB
Positive regulation of nuclear cell cycle DNA replication Source: UniProtKB
Cell division Source: UniProtKB-KW
DNA replication Source: Reactome
DNA replication initiation Source: Reactome
Double-strand break repair via break-induced replication Source: GO_Central
G1/S transition of mitotic cell cycle Source: ProtInc
Negative regulation of G0 to G1 transition Source: Reactome
Peptidyl-serine phosphorylation Source: GO_Central
Positive regulation of cell population proliferation Source: HGNC-UCL
Positive regulation of G2/M transition of mitotic cell cycle Source: UniProtKB
Positive regulation of nuclear cell cycle DNA replication Source: UniProtKB
Cellular Location
Nucleus
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Anti-CDC7 antibodies
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Target: CDC7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: DCS-342
Application*: WB, E, IF, IP
Target: CDC7
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG574
Application*: WB, F
Target: CDC7
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: Full Length
Tag: GST Tag
Target: CDC7
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: Full Length
Tag: GST Tag
Target: CDC7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: C0333
Application*: WB, P, IF, IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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