CENPV

CENPV (Centromere Protein V) is a Protein Coding gene. Diseases associated with CENPV include Intracranial Primitive Neuroectodermal Tumor and Diffuse Glomerulonephritis. Gene Ontology (GO) annotations related to this gene include carbon-sulfur lyase activity. An important paralog of this gene is CENPVL3.

Full Name

centromere protein V

Function

Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis.

Biological Process

Ameboidal-type cell migration Source: MGI
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Centromere complex assembly Source: UniProtKB
Pericentric heterochromatin assembly Source: UniProtKB
Positive regulation of cytokinesis Source: UniProtKB
Regulation of chromosome organization Source: UniProtKB

Cellular Location

Spindle; Nucleus; Kinetochore. Enriched at the nuclear periphery and around the nucleolus (PubMed:12196509). In mitotic cells, localizes to kinetochores from prometaphase to metaphase (PubMed:18772885). At anaphase onset, transfers to the spindle midzone and then to the mid-body in telophase and cytokinesis (PubMed:18772885).

Anti-CENPV antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-CENPV Recombinant Antibody (CBFYC-1722) (CBMAB-C1784-FY)

Datasheet

SDS

Target: CENPV

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYC-1722

Application*: E, IC, IF, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)