CLC

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008]
Full Name
Charcot-Leyden Crystal Galectin
Function
Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).
Biological Process
Multicellular organism development Source: ProtInc
Regulation of activated T cell proliferation Source: UniProtKB
Regulation of T cell anergy Source: UniProtKB
Regulation of T cell cytokine production Source: UniProtKB
T cell apoptotic process Source: UniProtKB
Cellular Location
Cytosol; Cytoplasmic granule. Localized in granules from where it may be secreted or transported to other locations in the cell.
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Anti-CLC antibodies

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Mouse Anti-CLC Recombinant Antibody (CBYCL-112) (CBMAB-L0013-YC)

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Target: CLC
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYCL-112
Application*: E
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Mouse Anti-CLC Recombinant Antibody (CBYJL-148) (CBMAB-L0219-YJ)

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Target: CLC
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-148
Application*: E
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Mouse Anti-CLC Recombinant Antibody (CBWJC-2755) (CBMAB-C3868WJ)

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Target: CLC
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBWJC-2755
Application*: IF, IH, WB, IP
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Mouse Anti-CLC Recombinant Antibody (G1101) (CBMAB-G1101-LY)

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Target: CLC
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: G1101
Application*: WB, F, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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