CYB5A

CYB5A (Cytochrome B5 Type A) is a Protein Coding gene. Diseases associated with CYB5A include Methemoglobinemia Type Iv and Adrenal Hyperplasia, Congenital, Due To 17-Alpha-Hydroxylase Deficiency. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include enzyme binding and cytochrome-c oxidase activity. An important paralog of this gene is CYB5B.
Full Name
Cytochrome B5 Type A
Function
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
Biological Process
L-ascorbic acid metabolic process Source: Reactome
Protein insertion into ER membrane Source: Reactome
Response to cadmium ion Source: Ensembl
Cellular Location
Isoform 1: Endoplasmic reticulum membrane; Microsome membrane
Isoform 2: Cytoplasm
Involvement in disease
Methemoglobinemia and ambiguous genitalia (METAG):
An autosomal recessive disorder characterized by sex steroid deficiency but normal glucocorticoid and mineralocorticoid reserve, male undermasculinization, absent or disturbed pubertal development, decreased levels of erythrocyte cytochrome B5, and excessive amounts of methemoglobin in blood cells resulting in cyanosis and hypoxia.
Topology
Helical: 109-131
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Anti-CYB5A antibodies

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Mouse Anti-CYB5A Recombinant Antibody (CBXC-1912) (CBMAB-C3795-CQ)

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Target: CYB5A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-1912
Application*: E, WB, IH
Datasheet SDS

Mouse Anti-CYB5A Recombinant Antibody (CBFYC-2551) (CBMAB-C2625-FY)

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Target: CYB5A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-2551
Application*: E, WB
Datasheet SDS

Mouse Anti-CYB5A Recombinant Antibody (CBYY-C3177) (V2LY-0125-LY832)

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Target: CYB5A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C3177
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CYB5A Recombinant Antibody (4C2) (V2LY-0125-LY830)

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Target: CYB5A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C2
Application*: E, P, WB, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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