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DEPDC1

DEPDC1 (DEP Domain Containing 1) is a Protein Coding gene. Diseases associated with DEPDC1 include Bladder Cancer. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is DEPDC1B.
Full Name
DEP domain containing 1
Function
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Biological Process
Intracellular signal transduction Source: InterPro
Negative regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of GTPase activity Source: GOC
Cellular Location
Nucleus. Colocalizes with ZNF224 at the nucleus.
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Anti-DEPDC1 antibodies

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Mouse Anti-DEPDC1 Recombinant Antibody (6H1) (CBMAB-A2187-LY)

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Target: DEPDC1
Host: Mouse
Antibody Isotype: IgG2a, λ
Specificity: Human
Clone: 6H1
Application*: WB, E
Datasheet SDS

Mouse Anti-DEPDC1 Recombinant Antibody (6H1) (V2LY-0425-LY195)

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Target: DEPDC1
Host: Mouse
Antibody Isotype: IgG2a, λ
Specificity: Human
Clone: 6H1
Application*: WB, IP, IF, E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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