loading...

DPPA4

DPPA4 is a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified.

Full Name

Developmental Pluripotency Associated 4

Function

May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.

Biological Process

Lung-associated mesenchyme development Source: Ensembl
System development Source: GO_Central

Cellular Location

Nucleus. Associated with transcriptionally active chromatin.

View more

Anti-DPPA4 antibodies

+ Filters

Loading...

Mouse Anti-DPPA4 Recombinant Antibody (1E12) (V2LY-0425-LY882)

Compare

Target: DPPA4

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1E12

Application*: WB

Mouse Anti-DPPA4 Recombinant Antibody (1C1) (V2LY-0425-LY881)

Compare

Target: DPPA4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1C1

Application*: IF, WB

Mouse Anti-DPPA4 Recombinant Antibody (2F6) (CBMAB-D1628-YC)

Compare

Target: DPPA4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2F6

Application*: F, WB

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry