Sign in or Register   Sign in or Register
  |  

DPYSL3

DPYSL3 (Dihydropyrimidinase Like 3) is a Protein Coding gene. Diseases associated with DPYSL3 include Prostate Lymphoma and Hypertensive Encephalopathy. Among its related pathways are Semaphorin interactions and Developmental Biology. Gene Ontology (GO) annotations related to this gene include hydrolase activity and phosphoprotein binding. An important paralog of this gene is CRMP1.
Full Name
dihydropyrimidinase-like 3
Function
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Biological Process
Actin crosslink formation Source: UniProtKB
Actin filament bundle assembly Source: UniProtKB
Cellular response to cytokine stimulus Source: UniProtKB
Negative regulation of cell migration Source: UniProtKB
Negative regulation of neuron projection development Source: UniProtKB
Neuron development Source: Ensembl
Positive regulation of filopodium assembly Source: UniProtKB
Positive regulation of neuron projection development Source: UniProtKB
Response to axon injury Source: UniProtKB
Cellular Location
Cytoplasm; Growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
PTM
Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.

Anti-DPYSL3 antibodies

Loading...
Target: DPYSL3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B8
Application*: E, P, WB
Target: DPYSL3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10C8
Application*: E, WB
Target: DPYSL3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR7592(B)
Application*: WB
Target: DPYSL3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR7593(B)
Application*: IF, IP, WB
Target: DPYSL3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 9G340
Application*: E, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
Go to
Compare