FTMT
FTMT (Ferritin Mitochondrial) is a Protein Coding gene. Diseases associated with FTMT include Friedreich Ataxia 1 and Restless Legs Syndrome. Among its related pathways are Ferroptosis. Gene Ontology (GO) annotations related to this gene include ferric iron binding and ferroxidase activity. An important paralog of this gene is FTH1.
Full Name
ferritin mitochondrial
Function
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Biological Process
Cellular iron ion homeostasis Source: BHF-UCL
Intracellular sequestering of iron ion Source: GO_Central
Iron ion transport Source: InterPro
Positive regulation of aconitate hydratase activity Source: BHF-UCL
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of lyase activity Source: BHF-UCL
Positive regulation of succinate dehydrogenase activity Source: BHF-UCL
Intracellular sequestering of iron ion Source: GO_Central
Iron ion transport Source: InterPro
Positive regulation of aconitate hydratase activity Source: BHF-UCL
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of lyase activity Source: BHF-UCL
Positive regulation of succinate dehydrogenase activity Source: BHF-UCL
Cellular Location
Mitochondrion
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Anti-FTMT antibodies
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Target: FTMT
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6G3
Application*: WB, E
Target: FTMT
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3227
Application*: E, WB
Target: FTMT
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0951
Application*: WB, IP, E
Target: FTMT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 6G3
Application*: WB
Target: FTMT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3227
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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