GFRA3
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.
Full Name
Gdnf Family Receptor Alpha 3
Function
Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.
Biological Process
Nervous system development Source: GO_Central
Neuron migration Source: Ensembl
Peripheral nervous system development Source: ProtInc
Signal transduction Source: ProtInc
Sympathetic nervous system development Source: Ensembl
Neuron migration Source: Ensembl
Peripheral nervous system development Source: ProtInc
Signal transduction Source: ProtInc
Sympathetic nervous system development Source: Ensembl
Cellular Location
Cell membrane
PTM
N-glycosylated.
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Anti-GFRA3 antibodies
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CompareTarget: GFRA3
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLG1-3166
Application*: WB
Target: GFRA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 118
Application*: E, WB
Target: GFRA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 111004
Application*: WB
Target: GFRA3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-379
Tag: His Tag
Target: GFRA3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-379
Tag: hFc Tag
Target: GFRA3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-382
Tag: His Tag
Target: GFRA3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-382
Tag: His & hFc Tag
Target: GFRA3
Host: Human
Antibody Isotype: IgG4, κ
Specificity: Human
Clone: CBLG1-3166
Application*: F
Target: GFRA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 118
Application*: WB, IP, IF, E
Target: GFRA3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: G0416
Application*: WB, IP, IF, E
Target: GFRA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 104
Application*: WB, IP
Target: GFRA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 101
Application*: E
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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