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GJC3

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010]

Full Name

Gap Junction Protein Gamma 3

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Biological Process

AV node cell to bundle of His cell communication by electrical coupling Source: GOC
Cell-cell signaling Source: GO_Central

Cellular Location

Cell membrane; Gap junction

Topology

Cytoplasmic: 1-22
Helical: 23-43
Extracellular: 44-75
Helical: 76-96
Cytoplasmic: 97-132
Helical: 133-153
Extracellular: 154-194
Helical: 195-215
Cytoplasmic: 216-279

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Anti-GJC3 antibodies

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Rabbit Anti-GJC3 Recombinant Antibody (EG1322) (CBMAB-EN1598-LY)

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Target: GJC3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1322

Application*: WB: 1:500~1:1000 ELISA: 1:40000

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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