GSTO1

The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Full Name
Glutathione S-Transferase Omega 1
Function
Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.
Biological Process
Cellular response to arsenic-containing substance Source: UniProtKB
Glutathione metabolic process Source: GO_Central
L-ascorbic acid metabolic process Source: UniProtKB
Negative regulation of ryanodine-sensitive calcium-release channel activity Source: BHF-UCL
Positive regulation of ryanodine-sensitive calcium-release channel activity Source: BHF-UCL
Positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion Source: BHF-UCL
Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Source: BHF-UCL
Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Source: BHF-UCL
Xenobiotic catabolic process Source: UniProtKB
Cellular Location
Cytosol
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Anti-GSTO1 antibodies

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Mouse Anti-GSTO1 Recombinant Antibody (CBLG1-2048) (CBMAB-G5537-LY)

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Target: GSTO1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBLG1-2048
Application*: WB, E
Datasheet SDS

Mouse Anti-GSTO1 Recombinant Antibody (CBLG1-2044) (CBMAB-G5533-LY)

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Target: GSTO1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-2044
Application*: WB, E, IH
Datasheet SDS

Mouse Anti-GSTO1 Recombinant Antibody (3D9) (CBMAB-G5525-LY)

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Target: GSTO1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D9
Application*: WB, E, IP
Datasheet SDS

Rabbit Anti-GSTO1 Recombinant Antibody (1B6) (CBMAB-G5524-LY)

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Target: GSTO1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: 1B6
Application*: WB, IF, IH
Datasheet SDS

Mouse Anti-GSTO1 Recombinant Antibody (6) (CBMAB-G5523-LY)

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Target: GSTO1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 6
Application*: WB, E, IP
Datasheet SDS

Rabbit Anti-GSTO1 Recombinant Antibody (
2C7) (V2LY-0725-LY737)

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Target: GSTO1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 2C7
Application*: E, WB, IH, IF
Datasheet SDS

GSTO1 Matched Antibody Pair (510) (APMAB-510LY)

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Target: GSTO1
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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