HMX2

The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]
Full Name
H6 Family Homeobox 2
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.
Biological Process
Brain development Source: Ensembl
Cell differentiation Source: UniProtKB-KW
Inner ear morphogenesis Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of mRNA splicing, via spliceosome Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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Anti-HMX2 antibodies

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Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B10
Application*: E, E
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D2
Application*: IF, E
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D7
Application*: WB, E
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1C8
Application*: WB, E
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-1586
Application*: E, P, WB
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1585
Application*: E, WB, IH
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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