HMX2
The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]
Full Name
H6 Family Homeobox 2
Function
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.
Biological Process
Brain development Source: Ensembl
Cell differentiation Source: UniProtKB-KW
Inner ear morphogenesis Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of mRNA splicing, via spliceosome Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cell differentiation Source: UniProtKB-KW
Inner ear morphogenesis Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of mRNA splicing, via spliceosome Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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Anti-HMX2 antibodies
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Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B10
Application*: E, E
Target: HMX2
Specificity: Human
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D2
Application*: IF, E
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D7
Application*: WB, E
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1C8
Application*: WB, E
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-1586
Application*: E, P, WB
Target: HMX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1585
Application*: E, WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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