HMX2

The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]

H6 Family Homeobox 2

Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.

Brain development Source: Ensembl
Cell differentiation Source: UniProtKB-KW
Inner ear morphogenesis Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of mRNA splicing, via spliceosome Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central

Nucleus