HOXA7
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.
                Full Name
                    homeobox A7
                Function
                    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
                Biological Process
                    Angiogenesis Source: UniProtKB
Anterior/posterior pattern specification Source: GO_Central
Embryonic skeletal system morphogenesis Source: Ensembl
Negative regulation of cell-matrix adhesion Source: UniProtKB
Negative regulation of keratinocyte differentiation Source: MGI
Negative regulation of leukocyte migration Source: UniProtKB
Negative regulation of monocyte differentiation Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Stem cell differentiation Source: Ensembl
                Anterior/posterior pattern specification Source: GO_Central
Embryonic skeletal system morphogenesis Source: Ensembl
Negative regulation of cell-matrix adhesion Source: UniProtKB
Negative regulation of keratinocyte differentiation Source: MGI
Negative regulation of leukocyte migration Source: UniProtKB
Negative regulation of monocyte differentiation Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Stem cell differentiation Source: Ensembl
Cellular Location
                    Nucleus
                
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                    Anti-HOXA7 antibodies
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        Target: HOXA7
                
                Host: Rabbit
                
                Antibody Isotype: IgG
                
                Specificity: Human, Mouse, Rat
                
                Clone: EG1544
                
                Application*: WB: 1:500~1:1000 ELISA: 1:40000
                
            Target: HOXA7
                
                Host: Mouse
                
                Antibody Isotype: IgG2a, κ
                
                Specificity: Human
                
                Clone: 2F2
                
                Application*: WB, E
                
            Target: HOXA7
                
                Host: Mouse
                
                Antibody Isotype: IgG1
                
                Specificity: Human
                
                Clone: 743C1a
                
                Application*: WB, DB
                
            Target: HOXA7
                
                Host: Mouse
                
                Antibody Isotype: IgG1
                
                Specificity: Human
                
                Clone: CBFYH-1752
                
                Application*: WB
                
            Target: HOXA7
                
                Host: Mouse
                
                Antibody Isotype: IgG1
                
                Specificity: Human
                
                Clone: CBFYH-1751
                
                Application*: DB
                
            Target: HOXA7
                
                Host: Mouse
                
                Antibody Isotype: IgG2a, κ
                
                Specificity: Human
                
                Clone: CBFYH-1750
                
                Application*: WB
                
            More Infomation
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For Research Use Only. Not For Clinical Use.
                    (P): Predicted
* Abbreviations 
- AActivation
 - AGAgonist
 - APApoptosis
 - BBlocking
 - BABioassay
 - BIBioimaging
 - CImmunohistochemistry-Frozen Sections
 - CIChromatin Immunoprecipitation
 - CTCytotoxicity
 - CSCostimulation
 - DDepletion
 - DBDot Blot
 
- EELISA
 - ECELISA(Cap)
 - EDELISA(Det)
 - ESELISpot
 - EMElectron Microscopy
 - FFlow Cytometry
 - FNFunction Assay
 - GSGel Supershift
 - IInhibition
 - IAEnzyme Immunoassay
 - ICImmunocytochemistry
 - IDImmunodiffusion
 - IEImmunoelectrophoresis
 
- IFImmunofluorescence
 - IGImmunochromatography
 - IHImmunohistochemistry
 - IMImmunomicroscopy
 - IOImmunoassay
 - IPImmunoprecipitation
 - ISIntracellular Staining for Flow Cytometry
 - LALuminex Assay
 - LFLateral Flow Immunoassay
 - MMicroarray
 - MCMass Cytometry/CyTOF
 - MDMeDIP
 
- MSElectrophoretic Mobility Shift Assay
 - NNeutralization
 - PImmunohistologyp-Paraffin Sections
 - PAPeptide Array
 - PEPeptide ELISA
 - PLProximity Ligation Assay
 - RRadioimmunoassay
 - SStimulation
 - SESandwich ELISA
 - SHIn situ hybridization
 - TCTissue Culture
 - WBWestern Blot
 
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