HOXB2

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. [provided by RefSeq, Jul 2008]

Full Name

Homeobox B2

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Biological Process

Anterior/posterior pattern specification Source: Ensembl
Blood circulation Source: ProtInc
Dorsal/ventral pattern formation Source: Ensembl
Embryonic skeletal system morphogenesis Source: Ensembl
Facial nerve structural organization Source: Ensembl
Morphogenesis of an epithelial sheet Source: Ensembl
Multicellular organism development Source: ProtInc
Neural nucleus development Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Rhombomere 3 development Source: Ensembl
Rhombomere 4 development Source: Ensembl

Cellular Location

Nucleus