HTATIP2

NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import.
Full Name
HIV-1 Tat interactive protein 2, 30kDa
Function
Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
Biological Process
Angiogenesis Source: UniProtKB-KW
Apoptotic process Source: UniProtKB-KW
Cell differentiation Source: UniProtKB-KW
Import into nucleus Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Positive regulation of programmed cell death Source: MGI
Positive regulation of transcription by RNA polymerase II Source: MGI
Protein autophosphorylation Source: MGI
Regulation of angiogenesis Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: ProtInc
Cellular Location
Cytoplasm; Nucleus envelope
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Anti-HTATIP2 antibodies

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Mouse Anti-HTATIP2 Recombinant Antibody (3E11) (CBMAB-A4148-LY)

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Target: HTATIP2
Host: Mouse
Antibody Isotype: IgG2a, λ
Specificity: Human
Clone: 3E11
Application*: E, E
Mouse Anti-HTATIP2 Recombinant Antibody (3E11)
Datasheet SDS

Rabbit Anti-HTATIP2 Recombinant Antibody (CBYJT-1385) (CBMAB-T0407-YJ)

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Target: HTATIP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-1385
Application*: WB, IP, P, F, IC, IF
Rabbit Anti-HTATIP2 Recombinant Antibody (CBYJT-1385)
Datasheet SDS

Mouse Anti-HTATIP2 Recombinant Antibody (CBYJT-1384) (CBMAB-T0406-YJ)

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Target: HTATIP2
Host: Mouse
Antibody Isotype: IgG2a, λ
Specificity: Human
Clone: CBYJT-1384
Application*: E
Mouse Anti-HTATIP2 Recombinant Antibody (CBYJT-1384)
Datasheet SDS

Mouse Anti-HTATIP2 Recombinant Antibody (CBYJT-1383) (CBMAB-T0405-YJ)

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Target: HTATIP2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1383
Application*: WB, IP, IF, E
Mouse Anti-HTATIP2 Recombinant Antibody (CBYJT-1383)
Datasheet SDS

Mouse Anti-HTATIP2 Recombinant Antibody (CBYJT-1382) (CBMAB-T0404-YJ)

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Target: HTATIP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-1382
Application*: WB, F, E, IC, IF
Mouse Anti-HTATIP2 Recombinant Antibody (CBYJT-1382)
Datasheet SDS

Mouse Anti-HTATIP2 (AA 1-242) Recombinant Antibody (CBFYH-2486) (CBMAB-H3501-FY)

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Target: HTATIP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-2486
Application*: E
Mouse Anti-HTATIP2 (AA 1-242) Recombinant Antibody (CBFYH-2486)
Datasheet SDS

Mouse Anti-HTATIP2 Recombinant Antibody (422D2a) (CBMAB-H3500-FY)

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Target: HTATIP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 422D2a
Application*: DB
Mouse Anti-HTATIP2 Recombinant Antibody (422D2a)
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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