IFNA2

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
Full Name
Interferon Alpha 2
Function
Produced by macrophages, IFN-alpha have antiviral activities.
Biological Process
Adaptive immune response Source: GO_Central
Apoptotic process Source: ProtInc
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cell-cell signaling Source: ProtInc
Cell surface receptor signaling pathway Source: ProtInc
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to virus Source: BHF-UCL
Humoral immune response Source: GO_Central
Inflammatory response Source: ProtInc
Natural killer cell activation involved in immune response Source: GO_Central
Negative regulation of gene expression Source: UniProtKB
Negative regulation of interleukin-13 production Source: UniProtKB
Negative regulation of interleukin-5 production Source: UniProtKB
Negative regulation of T cell differentiation Source: UniProtKB
Negative regulation of T-helper 2 cell cytokine production Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of viral entry into host cell Source: BHF-UCL
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: GO_Central
Positive regulation of phosphorylation Source: AgBase
Positive regulation of transcription, DNA-templated Source: AgBase
Positive regulation of tyrosine phosphorylation of STAT protein Source: BHF-UCL
Response to exogenous dsRNA Source: GO_Central
T cell activation involved in immune response Source: GO_Central
Cellular Location
Secreted
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Anti-IFNA2 antibodies

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Mouse Anti-IFNA2 Recombinant Antibody (2D6) (CBMAB-A4268-LY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2D6
Application*: WB, E
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I0819) (CBMAB-I1819-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0819
Application*: IC
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (24B10) (CBMAB-I0268-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 24B10
Application*: WB, IP
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (2E5) (CBMAB-A4252-LY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E5
Application*: E, E
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (4E3) (CBMAB-A4251-LY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4E3
Application*: WB, E
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (4E1) (CBMAB-A4250-LY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4E1
Application*: WB, E
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I1600) (CBMAB-I2770-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1600
Application*: E
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I1393) (CBMAB-I2563-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1393
Application*: WB, E, I, SE
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I0820) (CBMAB-I1820-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0820
Application*: BL
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I0765) (CBMAB-I1700-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0765
Application*: IS
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (N39) (CBMAB-I0925-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: N39
Application*: F, IF, BL, E, WB, N, BL, MC
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (N27) (CBMAB-I0924-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: N27
Application*: E., I, WB, F, E, IF, MC, BL
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (KT5) (CBMAB-I0794-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: KT5
Application*: E, WB
Datasheet SDS

Rat Anti-IFNA2 Recombinant Antibody (F18) (CBMAB-I0269-YY)

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Target: IFNA2
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: F18
Application*: E, IH, C, FN, BL, N, F, R
Datasheet SDS

Rat Anti-IFNA2 Recombinant Antibody (237526) (CBMAB-I0267-YY)

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Target: IFNA2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 237526
Application*: WB
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I0097) (CBMAB-I0266-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0097
Application*: F, IF
Datasheet SDS

Mouse Anti-IFNA2 Recombinant Antibody (1F8) (CBMAB-I0265-YY)

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Target: IFNA2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1F8
Application*: E, WB
Datasheet SDS

IFNA2 Matched Antibody Pair (603) (APMAB-603LY)

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Target: IFNA2
Specificity: Human
Datasheet SDS

IFNA2 Matched Antibody Pair (602) (APMAB-602LY)

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Target: IFNA2
Specificity: Human
Datasheet SDS

IFNA2 Matched Antibody Pair (601) (APMAB-601LY)

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Target: IFNA2
Specificity: Human
Datasheet SDS

IFNA2 Matched Antibody Pair (600) (APMAB-600LY)

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Target: IFNA2
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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