Mouse Anti-IFNA2 Recombinant Antibody (N27) (CBMAB-I0924-YY)

Name: Mouse Anti-IFNA2 Recombinant Antibody (N27)
SKU: CBMAB-I0924-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

N27

Application

ELISA., Inhib, WB, FC, ELISA, IF, CyTOF, BL

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Preservative

0.05% sodium azide

Concentration

0.1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Interferon Alpha 2

Introduction

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold.

Entrez Gene ID

3440

UniProt ID

P01563

Alternative Names

Interferon Alpha 2

Function

Produced by macrophages, IFN-alpha have antiviral activities.

Biological Process

Adaptive immune response Source: GO_Central
Apoptotic process Source: ProtInc
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cell-cell signaling Source: ProtInc
Cell surface receptor signaling pathway Source: ProtInc
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to virus Source: BHF-UCL
Humoral immune response Source: GO_Central
Inflammatory response Source: ProtInc
Natural killer cell activation involved in immune response Source: GO_Central
Negative regulation of gene expression Source: UniProtKB
Negative regulation of interleukin-13 production Source: UniProtKB
Negative regulation of interleukin-5 production Source: UniProtKB
Negative regulation of T cell differentiation Source: UniProtKB
Negative regulation of T-helper 2 cell cytokine production Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of viral entry into host cell Source: BHF-UCL
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: GO_Central
Positive regulation of phosphorylation Source: AgBase
Positive regulation of transcription, DNA-templated Source: AgBase
Positive regulation of tyrosine phosphorylation of STAT protein Source: BHF-UCL
Response to exogenous dsRNA Source: GO_Central
T cell activation involved in immune response Source: GO_Central

Cellular Location

Secreted

Verkaaik, M., Javad, W. M., Qi, H., van Helden-Meeuwsen, C. G., Huijser, E., van den Berg, L., ... & Versnel, M. A. (2022). PO. 3.67 Measuring IFNA2 levels by a single-molecule array in clinical practice of childhood-onset sle patients does matter; results from a single center longitudinal study.

Wang, S., Chen, S. N., Sun, Z., Pang, A. N., Wang, S., Liu, L. H., ... & Nie, P. (2021). Four type I IFNs, IFNa1, IFNa2, IFNb, IFNc, and their receptor usage in an osteoglossomorph fish, the Asian arowana, Scleropages formosus. Fish & Shellfish Immunology, 117, 70-81.

Liu, X., Zhang, Y., Liang, H., Zhang, Y., & Xu, Y. (2020). MicroRNA-499-3p inhibits proliferation and promotes apoptosis of retinal cells in diabetic retinopathy through activation of the TLR4 signaling pathway by targeting IFNA2. Gene, 741, 144539.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

IFNA2 Matched Antibody Pair (600) (CAT#: APMAB-600LY)

IFNA2 Matched Antibody Pair (601) (CAT#: APMAB-601LY)

IFNA2 Matched Antibody Pair (602) (CAT#: APMAB-602LY)

IFNA2 Matched Antibody Pair (603) (CAT#: APMAB-603LY)

Related Products

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Rat Anti-IFNA2 Recombinant Antibody (237526) (CAT#: CBMAB-I0267-YY)

Mouse Anti-IFNA2 Recombinant Antibody (2E5) (CAT#: CBMAB-A4252-LY)

Mouse Anti-IFNA2 Recombinant Antibody (KT5) (CAT#: CBMAB-I0794-YY)

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I0765) (CAT#: CBMAB-I1700-YY)

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I1600) (CAT#: CBMAB-I2770-YY)

IFNA2 Matched Antibody Pair (602) (CAT#: APMAB-602LY)

Mouse Anti-IFNA2 Recombinant Antibody (N39) (CAT#: CBMAB-I0925-YY)

Mouse Anti-IFNA2 Recombinant Antibody (4E1) (CAT#: CBMAB-A4250-LY)

Mouse Anti-IFNA2 Recombinant Antibody (1F8) (CAT#: CBMAB-I0265-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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