ILVBL
The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria, yeast, and plants. The highest degree of similarity is found with bacterial acetolactate synthases (AHAS), which are enzymes that catalyze the first step in branched-chain amino acid biosynthesis.
Full Name
IlvB Acetolactate Synthase Like
Function
Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the phytosphingosine degradation pathway.
Biological Process
Fatty acid alpha-oxidationManual Assertion Based On ExperimentIDA:UniProtKB
Isoleucine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Valine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Isoleucine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Valine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endoplasmic reticulum membrane
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Anti-ILVBL antibodies
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Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Rat, Monkey
Clone: CBYY-I2131
Application*: WB, IH, IF, F
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I2122
Application*: WB, F
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I2080
Application*: WB, IH, IF, F
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Monkey
Clone: CBYY-I2045
Application*: WB, IH
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I1985
Application*: WB, IH, IF, F
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I1889
Application*: WB, IH, F
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0917
Application*: F, IF, P, WB
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Rat, Monkey
Clone: 8B12
Application*: WB, F, IH, IF, P
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Rat, Monkey
Clone: 8A12
Application*: F, IF, P, WB
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6G9
Application*: F, WB
Target: ILVBL
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2F1
Application*: IF, F, IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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