JAG2

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
JAG2
Function
Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity).
Biological Process
Auditory receptor cell fate commitmentBy SimilarityISS:UniProtKB
Cell differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Epithelial cell apoptotic process involved in palatal shelf morphogenesisIEA:Ensembl
Gamma-delta T cell differentiationIEA:Ensembl
In utero embryonic developmentIEA:Ensembl
Morphogenesis of embryonic epitheliumIEA:Ensembl
Notch signaling pathway1 PublicationNAS:UniProtKB
Odontogenesis of dentin-containing toothIEA:Ensembl
Positive regulation of Notch signaling pathwayISS:UniProtKB
Regulation of cell adhesionIEA:Ensembl
Regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Respiratory system processIEA:Ensembl
Skeletal system developmentIEA:Ensembl
SpermatogenesisManual Assertion Based On ExperimentIEP:UniProtKB
T cell differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Thymic T cell selectionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 27-1080
Helical: 1081-1101
Cytoplasmic: 1102-1238
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Anti-JAG2 antibodies

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Rabbit Anti-JAG2 Recombinant Antibody (7H31) (CBMAB-0265-WJ)

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Target: JAG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 7H31
Application*: IP, WB
Datasheet SDS

Armenian Hamster Anti-JAG2 Recombinant Antibody (HMJ2-1) (CBMAB-1045-LY)

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Target: JAG2
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: HMJ2-1
Application*: N
Functional Assay
Datasheet SDS

JAG2 Matched Antibody Pair (654) (APMAB-654LY)

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Target: JAG2
Specificity: Human
Datasheet SDS

Rabbit Anti-JAG2 Recombinant Antibody (C83A8) (CBMAB-CP1244-LY)

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Target: JAG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: C83A8
Application*: WB, IP
Datasheet SDS

Hamster Anti-JAG2 Recombinant Antibody (CBWJJ-013) (CBMAB-0471-WJ)

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Target: JAG2
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBWJJ-013
Application*: IH
Datasheet SDS

Hamster Anti-JAG2 Recombinant Antibody (CBWJJ-012) (CBMAB-0470-WJ)

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Target: JAG2
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBWJJ-012
Application*: F, IH
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (CBWJJ-010) (CBMAB-0468-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJJ-010
Application*: WB, E
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (CBWJJ-009) (CBMAB-0467-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJJ-009
Application*: WB
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (CBWJJ-008) (CBMAB-0466-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJJ-008
Application*: E
Datasheet SDS

Rabbit Anti-JAG2 Recombinant Antibody (CBWJJ-007) (CBMAB-0465-WJ)

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Target: JAG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJJ-007
Application*: IP, WB
Datasheet SDS

Rabbit Anti-JAG2 Recombinant Antibody (CBWJJ-006) (CBMAB-0464-WJ)

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Target: JAG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJJ-006
Application*: E, IP, WB
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (MHJ2-523) (CBMAB-0383-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: MHJ2-523
Application*: F
Datasheet SDS

Rabbit Anti-JAG2 Recombinant Antibody (K.902.6) (CBMAB-0378-WJ)

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Target: JAG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: K.902.6
Application*: IP, WB
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (F-4) (CBMAB-0353-WJ)

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Target: JAG2
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: F-4
Application*: WB, IP, IF, E
Datasheet SDS

Rabbit Anti-JAG2 Recombinant Antibody (7H30) (CBMAB-0264-WJ)

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Target: JAG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: 7H30
Application*: WB, IP
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (4F10) (CBMAB-0216-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F10
Application*: WB, IP, E
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (1F2) (CBMAB-0096-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Pig, Fish, Goat, Cattle, Hamster, Rabbit, Mouse, Human, Chicken
Clone: 1F2
Application*: E, WB
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (1D11) (CBMAB-0088-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1D11
Application*: E, WB
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (1C5) (CBMAB-0086-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C5
Application*: E, WB
Datasheet SDS

Hamster Anti-JAG2 Recombinant Antibody (12G33) (CBMAB-0042-WJ)

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Target: JAG2
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: 12G33
Application*: F, IH
Datasheet SDS

Mouse Anti-JAG2 Recombinant Antibody (11n117) (CBMAB-0037-WJ)

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Target: JAG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: 11n117
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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