KCNK10

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
Full Name
potassium channel, subfamily K, member 10
Function
Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
Biological Process
MemoryIEA:Ensembl
Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Signal transduction1 PublicationNAS:ProtInc
Stabilization of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-71
Helical: 72-92
Pore-forming: 154-180
Helical: 182-202
Cytoplasmic: 203-233
Helical: 234-254
Pore-forming: 263-294
Helical: 299-319
Cytoplasmic: 320-538
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Anti-KCNK10 antibodies

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Mouse Anti-KCNK10 Recombinant Antibody (1C1) (CBMAB-K0587-LY)

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Target: KCNK10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C1
Application*: E, WB
Datasheet SDS

Human KCNK10 ELISA Kit (V2LY-0626-LY1934)

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Target: KCNK10
Sensitivity: 0.088 ng/mL
Detection Range: 0.2-60 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Mouse Anti-KCNK10 Recombinant Antibody (CBYJT-1410) (CBMAB-T0432-YJ)

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Target: KCNK10
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1410
Application*: WB, IP, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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