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Mouse Anti-KCNK10 Recombinant Antibody (CBYJT-1410) (CBMAB-T0432-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to KCNK10 (Potassium Two Pore Domain Channel Subfamily K Member 10). The antibody can be used for immunoassay techniques, such as WB, IP, ELISA.
See all KCNK10 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1410
Antibody Isotype
IgG
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
potassium channel, subfamily K, member 10
Introduction
KCNK10 belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics.
Entrez Gene ID
54207
UniProt ID
P57789
Alternative Names
Potassium Two Pore Domain Channel Subfamily K Member 10; Potassium Channel, Two Pore Domain Subfamily K, Member 10; Outward Rectifying Potassium Channel Protein TREK-2; Protein Phosphatase 1, Regulatory Subunit 97; Potassium Channel, Subfamily K, Member 10; TREK-2 K(+) Channel Subunit; TREK2; Potassium Channel Subfamily K Member 10
Function
Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
Biological Process
MemoryIEA:Ensembl
Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Signal transduction1 PublicationNAS:ProtInc
Stabilization of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-71
Helical: 72-92
Pore-forming: 154-180
Helical: 182-202
Cytoplasmic: 203-233
Helical: 234-254
Pore-forming: 263-294
Helical: 299-319
Cytoplasmic: 320-538
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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