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KCNK12

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.

Full Name

potassium two pore domain channel subfamily K member 12

Function

Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity).

Biological Process

Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Stabilization of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-38
Helical: 39-59
Pore-forming: 114-134
Helical: 145-165
Cytoplasmic: 166-212
Helical: 213-233
Pore-forming: 243-263
Helical: 282-302
Cytoplasmic: 303-430

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Anti-KCNK12 antibodies

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Human KCNK12 ELISA Kit (V2LY-0626-LY1935)

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Target: KCNK12

Sensitivity: 0.01 ng/mL

Detection Range: 0.02-4.5 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

Rabbit Anti-KCNK12 Recombinant Antibody (EG1763) (CBMAB-EN2102-LY)

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Target: KCNK12

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1763

Application*: WB: 1:500~1:1000 ELISA: 1:40000

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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