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Rabbit Anti-KCNK12 Recombinant Antibody (EG1763) (CBMAB-EN2102-LY)

The product is antibody recognizes KCNK12. The antibody EG1763 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:40000.
See all KCNK12 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1763
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from C-terminal of human KCNK12.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
potassium two pore domain channel subfamily K member 12
Introduction
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
Entrez Gene ID
Human56660
Mouse210741
Rat64119
UniProt ID
HumanQ9HB15
MouseQ76M80
RatQ9ERS1
Alternative Names
THIK2; THIK-2; K2p12.1
Function
Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity).
Biological Process
Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Stabilization of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-38
Helical: 39-59
Pore-forming: 114-134
Helical: 145-165
Cytoplasmic: 166-212
Helical: 213-233
Pore-forming: 243-263
Helical: 282-302
Cytoplasmic: 303-430
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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