Rabbit Anti-KCNK12 Recombinant Antibody (EG1763) (CBMAB-EN2102-LY)

Name: Rabbit Anti-KCNK12 Recombinant Antibody (EG1763)
SKU: CBMAB-EN2102-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1763

Application

WB: 1:500~1:1000 ELISA: 1:40000

Immunogen

The antibody was produced against synthesized peptide derived from C-terminal of human KCNK12.

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

potassium two pore domain channel subfamily K member 12

Introduction

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.

Entrez Gene ID

Human	56660
Mouse	210741
Rat	64119

UniProt ID

Human	Q9HB15
Mouse	Q76M80
Rat	Q9ERS1

Alternative Names

THIK2; THIK-2; K2p12.1

Function

Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity).

Biological Process

Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Stabilization of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-38
Helical: 39-59
Pore-forming: 114-134
Helical: 145-165
Cytoplasmic: 166-212
Helical: 213-233
Pore-forming: 243-263
Helical: 282-302
Cytoplasmic: 303-430

Han, S., Li, H., Zhang, W., He, J., & Yan, T. (2023). KCNK12 as a novel immune-related biomarker to reveal the crosstalk between COVID19 and stroke.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Human KCNK12 ELISA Kit (CAT#: V2LY-0626-LY1935)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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