KIF23

The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Full Name
Kinesin Family Member 23
Function
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
Biological Process
Microtubule-based movementManual Assertion Based On ExperimentIBA:GO_Central
Mitotic cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB
Mitotic spindle elongationManual Assertion Based On ExperimentTAS:ProtInc
Mitotic spindle midzone assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus; Cytoplasm, cytoskeleton, spindle; Midbody, Midbody ring. Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.
PTM
Ubiquitinated. Deubiquitinated by USP8/UBPY.
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Anti-KIF23 antibodies

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Rabbit Anti-KIF23 Recombinant Antibody (A759) (CBMAB-AP11115LY)

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Target: KIF23
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A759
Application*: ICC, IF, WB
Datasheet SDS

Recombinant Rabbit Anti-KIF23 Antibody (CBAb144) (CBMAB-Ab144-LY)

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Target: KIF23
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBAb144
Application*: WB, IF
Datasheet SDS

Rabbit Anti-KIF23 Recombinant Antibody (CBFYM-0300) (CBMAB-M0365-FY)

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Target: KIF23
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBFYM-0300
Application*: WB, IF
Datasheet SDS

Rabbit Anti-KIF23 Recombinant Antibody (A1115) (CBMAB-AP11863LY)

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Target: KIF23
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A1115
Application*: ICC, IF, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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