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KRT6B

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]
Full Name
keratin 6B
Biological Process
Ectoderm developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytosol
Extracellular exosome
Keratin filament
Involvement in disease
Pachyonychia congenita 4 (PC4):
An autosomal dominant genodermatosis characterized by hypertrophic nail dystrophy, painful and highly debilitating plantar keratoderma, oral leukokeratosis, and a variety of epidermal cysts.
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Anti-KRT6B antibodies

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Mouse Anti-KRT6B Recombinant Antibody (CBWJC-4070) (CBMAB-C5401WJ)

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Target: KRT6B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-4070
Application*: C, P, WB
Datasheet SDS

Rabbit Anti-KRT6B Recombinant Antibody (CBWJC-4067) (CBMAB-C5397WJ)

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Target: KRT6B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-4067
Application*: WB
Datasheet SDS

Mouse Anti-KRT6B Recombinant Antibody (LL020) (CBMAB-C3185WJ)

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Target: KRT6B
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Zebrafish
Clone: LL020
Application*: P, C, IC, WB
Datasheet SDS

Mouse Anti-KRT6B Recombinant Antibody (LHK6) (CBMAB-C3184WJ)

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Target: KRT6B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: LHK6
Application*: WB, E, IC, IP, P, C
Datasheet SDS

Rabbit Anti-KRT6B Recombinant Antibody (CBWJC-2296) (CBMAB-C3183WJ)

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Target: KRT6B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-2296
Application*: WB, IP, P, IC, F, IC
Datasheet SDS

Mouse Anti-KRT6B Recombinant Antibody (3B6) (CBMAB-K1937-LY)

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Target: KRT6B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3B6
Application*: E, WB
Datasheet SDS

Mouse Anti-KRT6B Recombinant Antibody (C11) (CBMAB-K0215-LY)

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Target: KRT6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Monkey
Clone: C11
Application*: IF, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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