METAP1

METAP1 (Methionyl Aminopeptidase 1) is a Protein Coding gene. Among its related pathways are Phototransduction and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include hydrolase activity and metalloexopeptidase activity. An important paralog of this gene is METAP1D.

Full Name

METHIONYL AMINOPEPTIDASE 1

Function

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.

Biological Process

N-terminal protein amino acid modification Source: HGNC-UCL
Peptidyl-methionine modification Source: HGNC-UCL
Platelet aggregation Source: UniProtKB
Protein initiator methionine removal Source: UniProtKB-UniRule
Regulation of translation Source: HGNC-UCL

Cellular Location

Cytoplasm

Anti-METAP1 antibodies

Mouse Anti-METAP1 Recombinant Antibody (CBFYM-2108) (CBMAB-M2290-FY)

Datasheet

SDS

Target: METAP1

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: CBFYM-2108

Application*: WB, IP, IF, E

Mouse Anti-METAP1 Recombinant Antibody (CBFYM-0626) (CBMAB-M0761-FY)

Datasheet

SDS

Target: METAP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-0626

Application*: WB

Mouse Anti-METAP1 Recombinant Antibody (CBFYM-0096) (CBMAB-M0107-FY)

Datasheet

SDS

Target: METAP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-0096

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)