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NGDN

Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).
Full Name
neuroguidin, EIF4E binding protein
Function
Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.
Biological Process
Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Regulation of translationIEA:UniProtKB-KW
Cellular Location
Nucleus
Nucleus, nucleolus
Chromosome, centromere
Cytoplasm
Cell projection, axon
Cell projection, dendrite
Cell projection, filopodium
Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity).
Translocated from nucleolus to nuclear foci in response to UV damage.
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Anti-NGDN antibodies

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Mouse Anti-NGDN Recombinant Antibody (8B5) (CBMAB-N2344-WJ)

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Target: NGDN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8B5
Application*: WB
Datasheet SDS

Mouse Anti-NGDN Recombinant Antibody (1H4) (CBMAB-N2343-WJ)

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Target: NGDN
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1H4
Application*: WB, IH
Datasheet SDS

Mouse Anti-NGDN Recombinant Antibody (1B8) (CBMAB-N2342-WJ)

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Target: NGDN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B8
Application*: WB, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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