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Mouse Anti-NGDN Recombinant Antibody (1H4) (CBMAB-N2343-WJ)

This product is a Mouse antibody that recognizes NGDN. The antibody 1H4 can be used for immunoassay techniques such as: WB, IHC .
See all NGDN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1H4
Antibody Isotype
IgG2b
Application
WB, IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1.00 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
neuroguidin, EIF4E binding protein
Introduction
Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]
Entrez Gene ID
UniProt ID
Alternative Names
Neuroguidin; Centromere Accumulated Nuclear Protein 1; Neuroguidin, EIF4E Binding Protein; EIF4E-Binding Protein; C14orf120; CANu1;
Function
Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.
Biological Process
Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Regulation of translationIEA:UniProtKB-KW
Cellular Location
Nucleus
Nucleus, nucleolus
Chromosome, centromere
Cytoplasm
Cell projection, axon
Cell projection, dendrite
Cell projection, filopodium
Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity).
Translocated from nucleolus to nuclear foci in response to UV damage.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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