Mouse Anti-NGDN Recombinant Antibody (1B8) (CBMAB-N2342-WJ)

Name: Mouse Anti-NGDN Recombinant Antibody (1B8)
SKU: CBMAB-N2342-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1B8

Application

WB, IHC

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1.00 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

neuroguidin, EIF4E binding protein

Introduction

Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]

Entrez Gene ID

25983

UniProt ID

Q8NEJ9

Alternative Names

Neuroguidin; Centromere Accumulated Nuclear Protein 1; Neuroguidin, EIF4E Binding Protein; EIF4E-Binding Protein; C14orf120; CANu1;

Function

Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.

Biological Process

Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Regulation of translationIEA:UniProtKB-KW

Cellular Location

Nucleus
Nucleus, nucleolus
Chromosome, centromere
Cytoplasm
Cell projection, axon
Cell projection, dendrite
Cell projection, filopodium
Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity).
Translocated from nucleolus to nuclear foci in response to UV damage.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-NGDN Recombinant Antibody (1H4) (CAT#: CBMAB-N2343-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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