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NUCB1

This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events.

Full Name

nucleobindin 1

Function

Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity).
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).

Biological Process

Small GTPase mediated signal transductionISS:UniProtKB

Cellular Location

Golgi apparatus, cis-Golgi network membrane
Cytoplasm
Secreted
A small fraction of the protein may be cytoplasmic.

PTM

O-glycosylated.

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Anti-NUCB1 antibodies

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Mouse Anti-NUCB1 Recombinant Antibody (1A3) (CBMAB-N3842-WJ)

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Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1A3

Application*: F, WB

Mouse Anti-NUCB1 Recombinant Antibody (1H8-2C11) (CBMAB-A6167-LY)

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Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1H8-2C11

Application*: WB, E

Mouse Anti-NUCB1 Recombinant Antibody (1A5) (CBMAB-1634-CN)

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Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: 1A5

Application*: WB, F, IF, IH, P

Mouse Anti-NUCB1 Recombinant Antibody (D-8) (CBMAB-N3847-WJ)

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Target: NUCB1

Host: Mouse

Specificity: Mouse

Clone: D-8

Application*: WB, IP, IF, E

Mouse Anti-NUCB1 Recombinant Antibody (2A5) (CBMAB-N3846-WJ)

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Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2A5

Application*: WB, IF

Mouse Anti-NUCB1 Recombinant Antibody (CBWJN-0283) (CBMAB-N3845-WJ)

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Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBWJN-0283

Application*: E, WB, P, IC

Mouse Anti-NUCB1 Recombinant Antibody (1G3) (CBMAB-N3844-WJ)

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Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1G3

Application*: WB, IH, IF

Mouse Anti-NUCB1 Recombinant Antibody (CBWJN-0078) (CBMAB-N3841-WJ)

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Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBWJN-0078

Application*: E, IF, IH, WB

Mouse Anti-NUCB1 Recombinant Antibody (4H9) (CBMAB-N0557-WJ)

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Target: NUCB1

Host: Mouse

Specificity: Human

Clone: 4H9

Application*: WB, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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