NUCB1

This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events.

Full Name

nucleobindin 1

Function

Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity).
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).

Biological Process

Small GTPase mediated signal transductionISS:UniProtKB

Cellular Location

Golgi apparatus, cis-Golgi network membrane
Cytoplasm
Secreted
A small fraction of the protein may be cytoplasmic.

PTM

O-glycosylated.

Anti-NUCB1 antibodies

Mouse Anti-NUCB1 Recombinant Antibody (1H8-2C11) (CBMAB-A6167-LY)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1H8-2C11

Application*: WB, E

Mouse Anti-NUCB1 Recombinant Antibody (D-8) (CBMAB-N3847-WJ)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Specificity: Mouse

Clone: D-8

Application*: WB, IP, IF, E

Mouse Anti-NUCB1 Recombinant Antibody (2A5) (CBMAB-N3846-WJ)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2A5

Application*: WB, IF

Mouse Anti-NUCB1 Recombinant Antibody (CBWJN-0283) (CBMAB-N3845-WJ)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBWJN-0283

Application*: E, WB, P, IC

Mouse Anti-NUCB1 Recombinant Antibody (1G3) (CBMAB-N3844-WJ)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1G3

Application*: WB, IH, IF

Mouse Anti-NUCB1 Recombinant Antibody (1A3) (CBMAB-N3842-WJ)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1A3

Application*: F, WB

Mouse Anti-NUCB1 Recombinant Antibody (CBWJN-0078) (CBMAB-N3841-WJ)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBWJN-0078

Application*: E, IF, IH, WB

Mouse Anti-NUCB1 Recombinant Antibody (4H9) (CBMAB-N0557-WJ)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Specificity: Human

Clone: 4H9

Application*: WB, E

Mouse Anti-NUCB1 Recombinant Antibody (1A5) (CBMAB-1634-CN)

Datasheet

SDS

Target: NUCB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: 1A5

Application*: WB, F, IF, IH, P

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)