NUCB1
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events.
Full Name
nucleobindin 1
Function
Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity).
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).
Biological Process
Small GTPase mediated signal transductionISS:UniProtKB
Cellular Location
Golgi apparatus, cis-Golgi network membrane
Cytoplasm
Secreted
A small fraction of the protein may be cytoplasmic.
Cytoplasm
Secreted
A small fraction of the protein may be cytoplasmic.
PTM
O-glycosylated.
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Anti-NUCB1 antibodies
+ Filters
Target: NUCB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A3
Application*: F, WB
Target: NUCB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1H8-2C11
Application*: WB, E
Target: NUCB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 1A5
Application*: WB, F, IF, IH, P
Target: NUCB1
Sensitivity: 0.0043 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: NUCB1
Host: Mouse
Specificity: Mouse
Clone: D-8
Application*: WB, IP, IF, E
Target: NUCB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A5
Application*: WB, IF
Target: NUCB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0283
Application*: E, WB, P, IC
Target: NUCB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G3
Application*: WB, IH, IF
Target: NUCB1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0078
Application*: E, IF, IH, WB
Target: NUCB1
Host: Mouse
Specificity: Human
Clone: 4H9
Application*: WB, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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