NUP43

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM

Full Name

nucleoporin 43kDa

Function

Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.

Biological Process

Cell cycleIEA:UniProtKB-KW
Cell divisionIEA:UniProtKB-KW
Chromosome segregationIEA:UniProtKB-KW
mRNA transportIEA:UniProtKB-KW
Nucleocytoplasmic transport1 PublicationIC:ComplexPortal
Protein transportIEA:UniProtKB-KW

Cellular Location

Chromosome, centromere, kinetochore
Nucleus, nuclear pore complex

Anti-NUP43 antibodies

Mouse Anti-NUP43 Recombinant Antibody (6H10) (CBMAB-N4004-WJ)

Datasheet

SDS

Target: NUP43

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 6H10

Application*: WB

Mouse Anti-NUP43 Recombinant Antibody (6F8) (CBMAB-N4003-WJ)

Datasheet

SDS

Target: NUP43

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6F8

Application*: WB, IH

Mouse Anti-NUP43 Recombinant Antibody (2G5) (CBMAB-N4001-WJ)

Datasheet

SDS

Target: NUP43

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G5

Application*: E, WB

Mouse Anti-NUP43 Recombinant Antibody (7E5) (CBMAB-N3999-WJ)

Datasheet

SDS

Target: NUP43

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 7E5

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)