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NUP43

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM

Full Name

nucleoporin 43kDa

Function

Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.

Biological Process

Cell cycleIEA:UniProtKB-KW
Cell divisionIEA:UniProtKB-KW
Chromosome segregationIEA:UniProtKB-KW
mRNA transportIEA:UniProtKB-KW
Nucleocytoplasmic transport1 PublicationIC:ComplexPortal
Protein transportIEA:UniProtKB-KW

Cellular Location

Chromosome, centromere, kinetochore
Nucleus, nuclear pore complex

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Anti-NUP43 antibodies

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Mouse Anti-NUP43 Recombinant Antibody (6H10) (CBMAB-N4004-WJ)

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Target: NUP43

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 6H10

Application*: WB

Mouse Anti-NUP43 Recombinant Antibody (6F8) (CBMAB-N4003-WJ)

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Target: NUP43

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6F8

Application*: WB, IH

Mouse Anti-NUP43 Recombinant Antibody (2G5) (CBMAB-N4001-WJ)

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Target: NUP43

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G5

Application*: E, WB

Mouse Anti-NUP43 Recombinant Antibody (7E5) (CBMAB-N3999-WJ)

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Target: NUP43

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 7E5

Application*: WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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