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Mouse Anti-NUP43 Recombinant Antibody (2G5) (CBMAB-N4001-WJ)

This product is a Mouse antibody that recognizes NUP43. The antibody 2G5 can be used for immunoassay techniques such as: ELISA, WB.
See all NUP43 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2G5
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
nucleoporin 43kDa
Introduction
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008]
Entrez Gene ID
348995
UniProt ID
Q8NFH3
Alternative Names
Nucleoporin 43; Nup107-160 Subcomplex Subunit Nup43; Nucleoporin 43kDa; P42; Nucleoporin Nup43; BA350J20.1;
Function
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
Biological Process
Cell cycleIEA:UniProtKB-KW
Cell divisionIEA:UniProtKB-KW
Chromosome segregationIEA:UniProtKB-KW
mRNA transportIEA:UniProtKB-KW
Nucleocytoplasmic transport1 PublicationIC:ComplexPortal
Protein transportIEA:UniProtKB-KW
Cellular Location
Chromosome, centromere, kinetochore
Nucleus, nuclear pore complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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