OR5AU1

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Full Name

Olfactory Receptor Family 5 Subfamily AU Member 1

Function

Odorant receptor.

Cellular Location

Cell membrane

Topology

Extracellular: 1-79
Helical: 80-100
Cytoplasmic: 101-116
Helical: 117-139
Extracellular: 140-150
Helical: 151-171
Cytoplasmic: 172-194
Helical: 195-215
Extracellular: 216-247
Helical: 248-268
Cytoplasmic: 269-290
Helical: 291-311
Extracellular: 312-322
Helical: 323-343
Cytoplasmic: 344-362