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OSBPL11

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.

Full Name

Oxysterol Binding Protein Like 11

Function

Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956).
Weakly binds 25-hydroxycholesterol (PubMed:17428193).

Biological Process

Fat cell differentiationManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of sequestering of triglycerideManual Assertion Based On ExperimentIMP:BHF-UCL

Cellular Location

Late endosome membrane
Golgi apparatus, trans-Golgi network membrane
Localizes at the Golgi-late endosome interface.

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Anti-OSBPL11 antibodies

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Mouse Anti-OSBPL11 Recombinant Antibody (7B3) (CBMAB-O0589-CQ)

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Target: OSBPL11

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Dog, Rat, Monkey

Clone: 7B3

Application*: WB

Mouse Anti-OSBPL11 Recombinant Antibody (6H9) (CBMAB-O0588-CQ)

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Target: OSBPL11

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Dog, Monkey

Clone: 6H9

Application*: IF, WB

Mouse Anti-OSBPL11 Recombinant Antibody (10F6) (CBMAB-O0586-CQ)

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Target: OSBPL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 10F6

Application*: IF, WB

Mouse Anti-OSBPL11 Recombinant Antibody (5A10) (CBMAB-O0585-CQ)

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Target: OSBPL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5A10

Application*: F, IH, P, WB

Mouse Anti-OSBPL11 Recombinant Antibody (6A6) (CBMAB-O0584-CQ)

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Target: OSBPL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6A6

Application*: F, IF, WB

Mouse Anti-OSBPL11 Recombinant Antibody (2C8) (CBMAB-O0583-CQ)

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Target: OSBPL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2C8

Application*: WB

Human OSBPL11 ELISA Kit (V2LY-0626-LY3786)

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Target: OSBPL11

Sensitivity: 0.025 ng/mL

Detection Range: 0.05-15 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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