OSBPL11

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
Full Name
Oxysterol Binding Protein Like 11
Function
Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956).
Weakly binds 25-hydroxycholesterol (PubMed:17428193).
Biological Process
Fat cell differentiationManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of sequestering of triglycerideManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Late endosome membrane
Golgi apparatus, trans-Golgi network membrane
Localizes at the Golgi-late endosome interface.
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Anti-OSBPL11 antibodies

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Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Rat, Monkey
Clone: 7B3
Application*: WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Monkey
Clone: 6H9
Application*: IF, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10F6
Application*: IF, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A10
Application*: F, IH, P, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A6
Application*: F, IF, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C8
Application*: WB
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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