OSBPL11
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
Full Name
Oxysterol Binding Protein Like 11
Function
Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956).
Weakly binds 25-hydroxycholesterol (PubMed:17428193).
Weakly binds 25-hydroxycholesterol (PubMed:17428193).
Biological Process
Fat cell differentiationManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of sequestering of triglycerideManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of sequestering of triglycerideManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Late endosome membrane
Golgi apparatus, trans-Golgi network membrane
Localizes at the Golgi-late endosome interface.
Golgi apparatus, trans-Golgi network membrane
Localizes at the Golgi-late endosome interface.
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Anti-OSBPL11 antibodies
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Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Rat, Monkey
Clone: 7B3
Application*: WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Monkey
Clone: 6H9
Application*: IF, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10F6
Application*: IF, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A10
Application*: F, IH, P, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A6
Application*: F, IF, WB
Target: OSBPL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C8
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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