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Mouse Anti-OSBPL11 Recombinant Antibody (2C8) (CBMAB-O0583-CQ)

This product is a mouse antibody that recognizes OSBPL11. The antibody 2C8 can be used for immunoassay techniques such as: WB.
See all OSBPL11 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2C8
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium Azide
Concentration
0.69 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Oxysterol Binding Protein Like 11
Introduction
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
Entrez Gene ID
UniProt ID
Alternative Names
Oxysterol Binding Protein Like 11; OSBP-Related Protein 11; ORP-11; OSBP12; ORP11; Oxysterol-Binding Protein-Related Protein 11; Oxysterol Binding Protein-Like 11; Testicular Tissue Protein Li 132; TCCCIA00292
Function
Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956).
Weakly binds 25-hydroxycholesterol (PubMed:17428193).
Biological Process
Fat cell differentiationManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of sequestering of triglycerideManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Late endosome membrane
Golgi apparatus, trans-Golgi network membrane
Localizes at the Golgi-late endosome interface.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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