Sign in or Register
  |  
P53

Dmp53 shares significant amino acid identity with the DNA-binding domain of p53, including conservation of key residues commonly mutated in human cancer. Like p53, overexpression of Dmp53 induces apoptosis, and inhibition of Dmp53 function renders cells resistant to X ray–induced apoptosis. In contrast to mammalian p53, Dmp53 overexpression does not induce a G1 cell cycle block, and inhibition of Dmp53 activity does not affect X ray–induced cell cycle arrest.

Anti-P53 antibodies

Loading...
'
Cat Product Name Target Host Antibody Isotype Cross Reactivity Clone Application*
CBMAB-Z0209-LY Mouse Anti-p53 Recombinant Antibody (6C4-C12-H10) p53 Mouse IgG2b Human 6C4-C12-H10 WB
CBMAB-0433-LY Mouse Anti-p53 Recombinant Antibody (7A4) p53 Mouse IgG1 Common fruit fly 7A4 IF, IH, IP, WB
CBMAB-0432-LY Mouse Anti-p53 Recombinant Antibody (25F4) p53 Mouse IgG2a Common fruit fly 25F4 IF, IH, IP, WB
CBMAB-1480CQ Mouse Anti-p53 Recombinant Antibody (H3) p53 Mouse IgG3 Common fruit fly H3 E, IP
CBMAB-1479CQ Mouse Anti-p53 Recombinant Antibody (H1) p53 Mouse IgG2a Common fruit fly H1 E, IP
CBMAB-Z0435-LY Mouse Anti-p53 Recombinant Antibody (2D10-1E9-1D3) p53 Mouse IgG1 Human 2D10-1E9-1D3 WB, P, IF
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)