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P53

Dmp53 shares significant amino acid identity with the DNA-binding domain of p53, including conservation of key residues commonly mutated in human cancer. Like p53, overexpression of Dmp53 induces apoptosis, and inhibition of Dmp53 function renders cells resistant to X ray–induced apoptosis. In contrast to mammalian p53, Dmp53 overexpression does not induce a G1 cell cycle block, and inhibition of Dmp53 activity does not affect X ray–induced cell cycle arrest.

Anti-P53 antibodies

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Mouse Anti-p53 Recombinant Antibody (2D10-1E9-1D3) (CBMAB-Z0435-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Human
Clone: 2D10-1E9-1D3
Application*: WB, P, IF

Mouse Anti-p53 Recombinant Antibody (H3) (CBMAB-1480CQ)

Target: p53
Host: Mouse
Antibody Isotype: IgG3
Cross Reactivity: Common fruit fly
Clone: H3
Application*: E, IP

Mouse Anti-p53 Recombinant Antibody (H1) (CBMAB-1479CQ)

Target: p53
Host: Mouse
Antibody Isotype: IgG2a
Cross Reactivity: Common fruit fly
Clone: H1
Application*: E, IP

Mouse Anti-p53 Recombinant Antibody (CBDH2122) (CBMAB-DH2122-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG2a, λ
Cross Reactivity: Drosophila
Clone: CBDH2122
Application*: IF, IHC, IP, WB

Mouse Anti-p53 Recombinant Antibody (CBDH2121) (CBMAB-DH2121-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG1, λ
Cross Reactivity: Drosophila
Clone: CBDH2121
Application*: IF, IHC, IP, WB

Mouse Anti-p53 Recombinant Antibody (6C4-C12-H10) (CBMAB-Z0209-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG2b
Cross Reactivity: Human
Clone: 6C4-C12-H10
Application*: WB

Mouse Anti-p53 Recombinant Antibody (CBDH2120) (CBMAB-DH2120-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG2a
Cross Reactivity: Drosophila
Clone: CBDH2120
Application*: ELISA, Gel Supershift, IP

Mouse Anti-p53 Recombinant Antibody (CBDH2119) (CBMAB-DH2119-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG3
Cross Reactivity: Drosophila
Clone: CBDH2119
Application*: ELISA, IP, WB

Mouse Anti-p53 Recombinant Antibody (7A4) (CBMAB-0433-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG1
Cross Reactivity: Common fruit fly
Clone: 7A4
Application*: IF, IH, IP, WB

Mouse Anti-p53 Recombinant Antibody (25F4) (CBMAB-0432-LY)

Target: p53
Host: Mouse
Antibody Isotype: IgG2a
Cross Reactivity: Common fruit fly
Clone: 25F4
Application*: IF, IH, IP, WB
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)