Mouse Anti-p53 Antibody (H3) (CBMAB-1480CQ)

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Basic Information

Host Animal
Mouse
Clone
H3
Application
ELISA, IP
Immunogen
Recombinant GST fusion protein of Drosophila p53
Specificity
Common fruit fly
Antibody Isotype
IgG3
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
p53
Introduction
Dmp53 shares significant amino acid identity with the DNA-binding domain of p53, including conservation of key residues commonly mutated in human cancer. Like p53, overexpression of Dmp53 induces apoptosis, and inhibition of Dmp53 function renders cells resistant to X ray–induced apoptosis. In contrast to mammalian p53, Dmp53 overexpression does not induce a G1 cell cycle block, and inhibition of Dmp53 activity does not affect X ray–induced cell cycle arrest.
Entrez Gene ID
UniProt ID
Alternative Names
CG10873; CG31325; CG33336; D-p53; Dm-P53; Dmel\CG33336; dmp53; Dmp53; DmP53; DMP53; dp53; Dp53; prac
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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