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PLPBP

PLPBP is a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin.

Full Name

Pyridoxal Phosphate Binding Protein

Function

Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

Cellular Location

cytoplasm
cytosol

Involvement in disease

Epilepsy, early-onset, vitamin B6-dependent (EPVB6D):
An autosomal recessive neurologic disorder characterized by seizures responsive to treatment with activated vitamin B6 and/or pyridoxine. Most patients show delayed psychomotor development, intellectual disability and learning disability. Seizures onset is in the first days or months of life.

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Anti-PLPBP antibodies

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Mouse Anti-PLPBP Recombinant Antibody (1G2) (CBMAB-P2169-YC)

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Target: PLPBP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1G2

Application*: F, IF, P, WB

Mouse Anti-PLPBP Recombinant Antibody (2G1) (CBMAB-A7083-LY)

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Target: PLPBP

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2G1

Application*: SE, E

Mouse Anti-PLPBP Recombinant Antibody (3A6) (CBMAB-P2171-YC)

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Target: PLPBP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3A6

Application*: F, P, WB

Mouse Anti-PLPBP Recombinant Antibody (2G1) (CBMAB-P2170-YC)

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Target: PLPBP

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2G1

Application*: E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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