PLPBP

PLPBP is a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin.

Full Name

Pyridoxal Phosphate Binding Protein

Function

Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

Cellular Location

cytoplasm
cytosol

Involvement in disease

Epilepsy, early-onset, vitamin B6-dependent (EPVB6D):
An autosomal recessive neurologic disorder characterized by seizures responsive to treatment with activated vitamin B6 and/or pyridoxine. Most patients show delayed psychomotor development, intellectual disability and learning disability. Seizures onset is in the first days or months of life.

Anti-PLPBP antibodies

Mouse Anti-PLPBP Recombinant Antibody (2G1) (CBMAB-A7083-LY)

Datasheet

SDS

Target: PLPBP

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2G1

Application*: SE, E

Mouse Anti-PLPBP Recombinant Antibody (3A6) (CBMAB-P2171-YC)

Datasheet

SDS

Target: PLPBP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3A6

Application*: F, P, WB

Mouse Anti-PLPBP Recombinant Antibody (2G1) (CBMAB-P2170-YC)

Datasheet

SDS

Target: PLPBP

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2G1

Application*: E

Mouse Anti-PLPBP Recombinant Antibody (1G2) (CBMAB-P2169-YC)

Datasheet

SDS

Target: PLPBP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1G2

Application*: F, IF, P, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)