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PLPBP

PLPBP is a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin.
Full Name
Pyridoxal Phosphate Binding Protein
Function
Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.
Cellular Location
cytoplasm
cytosol
Involvement in disease
Epilepsy, early-onset, vitamin B6-dependent (EPVB6D):
An autosomal recessive neurologic disorder characterized by seizures responsive to treatment with activated vitamin B6 and/or pyridoxine. Most patients show delayed psychomotor development, intellectual disability and learning disability. Seizures onset is in the first days or months of life.
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Anti-PLPBP antibodies

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Mouse Anti-PLPBP Recombinant Antibody (1G2) (CBMAB-P2169-YC)

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Target: PLPBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G2
Application*: F, IF, P, WB
Datasheet SDS

Mouse Anti-PLPBP Recombinant Antibody (2G1) (CBMAB-A7083-LY)

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Target: PLPBP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2G1
Application*: SE, E
Datasheet SDS

Mouse Anti-PLPBP Recombinant Antibody (3A6) (CBMAB-P2171-YC)

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Target: PLPBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A6
Application*: F, P, WB
Datasheet SDS

Mouse Anti-PLPBP Recombinant Antibody (2G1) (CBMAB-P2170-YC)

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Target: PLPBP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2G1
Application*: E
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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