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Mouse Anti-PLPBP Recombinant Antibody (2G1) (CBMAB-P2170-YC)

Provided herein is a Mouse monoclonal antibody against Human Pyridoxal Phosphate Binding Protein. The antibody can be used for immunoassay techniques, such as ELISA.
See all PLPBP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2G1
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
PROSC (NP_009129.1, 1-100 aa) partial recombinant protein with GST tag. Immunogen sequence: MWRAGSMSAE LGVGCALRAV NERVQQAVAR RPRDLPAIQP RLVAVSKTKP ADMVIEAYGH GQRTFGENYV QELLEKASNP KILSLCPEIK WHFIGHLQKQ
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-100

Target

Full Name
Pyridoxal Phosphate Binding Protein
Introduction
PLPBP is a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin.
Entrez Gene ID
11212
UniProt ID
O94903
Alternative Names
EPVB6D; PROSC
Function
Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.
Cellular Location
cytoplasm
cytosol
Involvement in disease
Epilepsy, early-onset, vitamin B6-dependent (EPVB6D):
An autosomal recessive neurologic disorder characterized by seizures responsive to treatment with activated vitamin B6 and/or pyridoxine. Most patients show delayed psychomotor development, intellectual disability and learning disability. Seizures onset is in the first days or months of life.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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