POLR3GL

POLR3GL (RNA Polymerase III Subunit G Like) is a protein coding gene. Among its related pathways are RNA Polymerase III Transcription Initiation and Pyrimidine metabolism (KEGG). Gene Ontology annotations related to this gene include RNA polymerase III activity. An important paralog of the gene is POLR3G.

Full Name

RNA Polymerase III Subunit G Like

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.

Biological Process

Transcription by RNA polymerase IIIManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Nucleus

Involvement in disease

Short stature, oligodontia, dysmorphic facies, and motor delay (SOFM):
An autosomal recessive disorder with phenotypic variability. The main clinical features include endosteal hyperostosis, short stature, oligodontia, mild facial dysmorphisms, and delayed motor development. Some patients show progeroid features.

Anti-POLR3GL antibodies

Mouse Anti-POLR3GL Recombinant Antibody (5E8) (CBMAB-P2376-YC)

Datasheet

SDS

Target: POLR3GL

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5E8

Application*: WB, IH, IF

Mouse Anti-POLR3GL Recombinant Antibody (2F11) (CBMAB-P2375-YC)

Datasheet

SDS

Target: POLR3GL

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2F11

Application*: WB, P

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)