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Mouse Anti-POLR3GL Recombinant Antibody (5E8) (CBMAB-P2376-YC)

Provided herein is a Mouse monoclonal antibody against Human RNA Polymerase III Subunit G Like. The antibody can be used for immunoassay techniques, such as WB, IHC, IF.
See all POLR3GL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5E8
Antibody Isotype
IgG1
Application
WB, IHC, IF

Basic Information

Immunogen
Full length human recombinant protein of human POLR3GL (NP_115681) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
RNA Polymerase III Subunit G Like
Introduction
POLR3GL (RNA Polymerase III Subunit G Like) is a protein coding gene. Among its related pathways are RNA Polymerase III Transcription Initiation and Pyrimidine metabolism (KEGG). Gene Ontology annotations related to this gene include RNA polymerase III activity. An important paralog of the gene is POLR3G.
Entrez Gene ID
84265
UniProt ID
Q9BT43
Alternative Names
RPC32HOM; flj32422
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Biological Process
Transcription by RNA polymerase IIIManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Involvement in disease
Short stature, oligodontia, dysmorphic facies, and motor delay (SOFM):
An autosomal recessive disorder with phenotypic variability. The main clinical features include endosteal hyperostosis, short stature, oligodontia, mild facial dysmorphisms, and delayed motor development. Some patients show progeroid features.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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