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POMZP3

This gene appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]

Full Name

POM (POM121 homolog, rat) and ZP3 fusion

Biological Process

Binding of sperm to zona pellucidaManual Assertion Based On ExperimentIBA:GO_Central
Egg coat formationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of acrosome reactionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

extracellular matrix
nuclear membrane
nucleoplasm

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Anti-POMZP3 antibodies

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Mouse Anti-POMZP3 Recombinant Antibody (CBYC-P515) (CBMAB-P2399-YC)

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Target: POMZP3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYC-P515

Application*: E, IH, WB

Mouse Anti-POMZP3 Recombinant Antibody (2E7) (CBMAB-P2398-YC)

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Target: POMZP3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2E7

Application*: E, P, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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