POMZP3
This gene appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]
Full Name
POM (POM121 homolog, rat) and ZP3 fusion
Biological Process
Binding of sperm to zona pellucidaManual Assertion Based On ExperimentIBA:GO_Central
Egg coat formationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of acrosome reactionManual Assertion Based On ExperimentIBA:GO_Central
Egg coat formationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of acrosome reactionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
extracellular matrix
nuclear membrane
nucleoplasm
nuclear membrane
nucleoplasm
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Anti-POMZP3 antibodies
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Target: POMZP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P515
Application*: E, IH, WB
Target: POMZP3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E7
Application*: E, P, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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