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Mouse Anti-POMZP3 Recombinant Antibody (2E7) (CBMAB-P2398-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2E7
Antibody Isotype
IgG1, κ
Application
ELISA, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
POM (POM121 homolog, rat) and ZP3 fusion
Introduction
POMZP3 appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain.
Entrez Gene ID
22932
UniProt ID
Q6PJE2
Alternative Names
POM-ZP3; POM121
Biological Process
Binding of sperm to zona pellucidaManual Assertion Based On ExperimentIBA:GO_Central
Egg coat formationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of acrosome reactionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
extracellular matrix
nuclear membrane
nucleoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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