PRSS16

PRSS16 is a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.

Serine Protease 16

Protease that may play a role in T-cell development.

Protein catabolic process1 PublicationNAS:UniProtKB
ProteolysisIEA:UniProtKB-KW

Cytoplasmic vesicle
Vesicular, either lysosomal or endosomal.