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PSPN

PSPN is a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations.

Full Name

Persephin

Function

Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.

Biological Process

Central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Secreted

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Anti-PSPN antibodies

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Mouse Anti-PSPN Recombinant Antibody (CBYC-P734) (CBMAB-P3278-YC)

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Target: PSPN

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYC-P734

Application*: WB, IC, P, C, E

Rat Anti-PSPN Recombinant Antibody (6H29) (CBMAB-P3277-YC)

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Target: PSPN

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: 6H29

Application*: WB

Mouse Anti-PSPN Recombinant Antibody (CBYC-P733) (CBMAB-P3276-YC)

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Target: PSPN

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYC-P733

Application*: IH, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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