RABV GP
Rabies virus is a neurotropic virus that causes rabies in humans and animals. Rabies transmission can occur through the saliva of animals and less commonly through contact with human saliva. Rabies virus, like many rhabdoviruses, has an extremely wide host range. In the wild it has been found infecting many mammalian species, while in the laboratory it has been found that birds can be infected, as well as cell cultures from mammals, birds, reptiles and insects.
Full Name
Rabies virus Glycoprotein
Function
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Cellular Location
Virion membrane
PTM
Glycosylated and palmitoylated by host. Glycosylation is crucial for glycoprotein export at the cell surface.
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Anti-RABV GP antibodies
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Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rabies Virus
Clone: 7E3
Application*: IF, WB, E
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rabies Virus
Clone: CBMC-C0385
Application*: E, IF, WB
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabies virus
Clone: RV1C5
Application*: E, IF, P
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabies Virus
Clone: CBMC-C0503
Application*: E, C
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabies Virus
Clone: CBMC-C0362
Application*: E, IC, IF
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rabies Virus
Clone: 9A10
Application*: E
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabies virus
Clone: 5B12
Application*: E
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabies virus
Clone: 4G4
Application*: N, E
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rabies Virus
Clone: 4F1
Application*: IF, WB, E
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabies Virus
Clone: 1C5
Application*: E, N, IF
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabies Virus
Clone: CBMC-C0319
Application*: E, IF, IH
Target: RABV GP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rabies Virus
Clone: CBMC-C0316
Application*: E, IF
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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